Evaluation of electrophysiological examinations for the diagnosis of carpal tunnel syndrome

To investigate the clinical significance of results in electrodiagnostic evaluations for carpal tunnel syndrome(CTS) and analyze the correlation between electrodiagnostic evaluations and physical examinations, 236 CTS patients and 96 healthy volunteers accepted electrodiagnostic evaluations. There were significant differences between CTS and control groups, mild and moderate patients, moderate and severe patients in CTS groups respectively, in terms of compound muscle action potential(CMAP), sensory conduction velocity of middle finger(SCV), distal motor latency(DML) difference between median nerve and ulnar nerve on the ring finger(△DML) (p < 0.05).△DML has larger area under curve of ROC curve (0.974) than CMAP, SCV and DML(0.748, 0.950, 0.958), then △DML could be included as valuable test for diagnosing and classification of carpal tunnel syndromes. There was low correlation between electrodiagnostic evaluations and physical examinations (rho < 0.4), so electrodiagnostic evaluation and physical examination should be combined to diagnose CTS. TYPE OF STUDY/LEVEL OF EVIDENCE: Diagnostic III.

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Publication Details

Journal
Journal of Orthopaedic Surgery and Research
Published
2025-07-19
DOI
https://doi.org/10.1186/s13018-025-06122-2
Citations
2
Primary Topic
Peripheral Nerve Disorders
Type
article
Field-Weighted Citation Impact
2.72

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article

Evaluation of electrophysiological examinations for the diagnosis of carpal tunnel syndrome

Jinjin Cao, Ailin Liu, Xi Chen, Rui Jing et al.
2 citations
Journal of Orthopaedic Surgery and Research
Peripheral Nerve Disorders
2.72
article

Evaluation of electrophysiological examinations for the diagnosis of carpal tunnel syndrome

Jinjin Cao, Ailin Liu, Xi Chen, Rui Jing, Jie Lao
article en
2 citations

Abstract

To investigate the clinical significance of results in electrodiagnostic evaluations for carpal tunnel syndrome(CTS) and analyze the correlation between electrodiagnostic evaluations and physical examinations, 236 CTS patients and 96 healthy volunteers accepted electrodiagnostic evaluations. There were significant differences between CTS and control groups, mild and moderate patients, moderate and severe patients in CTS groups respectively, in terms of compound muscle action potential(CMAP), sensory conduction velocity of middle finger(SCV), distal motor latency(DML) difference between median nerve and ulnar nerve on the ring finger(△DML) (p < 0.05).△DML has larger area under curve of ROC curve (0.974) than CMAP, SCV and DML(0.748, 0.950, 0.958), then △DML could be included as valuable test for diagnosing and classification of carpal tunnel syndromes. There was low correlation between electrodiagnostic evaluations and physical examinations (rho < 0.4), so electrodiagnostic evaluation and physical examination should be combined to diagnose CTS. TYPE OF STUDY/LEVEL OF EVIDENCE: Diagnostic III.

Journal of Orthopaedic Surgery and ResearchVol. 20(1)
Fudan University (CN), Xijing Hospital (CN), Huashan Hospital (CN), Shanghai Micro Electronics Equipment (China) (CN), Air Force Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 10%
Peripheral Nerve Disorders
2.72
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Evaluation of electrophysiological examinations for the diagnosis of carpal tunnel syndrome — Jinjin Cao, Ailin Liu, et al. · Journal of Orthopaedic Surgery and Research (2025) | TGRS Research Map | TGRS