Therapeutic reasoning in case reports: Insights into current reporting and learning opportunities

Although case reports have the potential to develop clinical reasoning skills, this opportunity is underused for therapeutic reasoning. Key aspects, such as a complete description of drug choices and the underlying rationale, are frequently omitted. This gap limits the educational value of case reports. We recommend incorporating a structured approach to therapeutic reasoning in case reports, such as elements of the World Health Organization 6-step method, to enhance their clarity, educational impact and practical relevance. There is also a role for clinical pharmacology journals to actively highlight and promote high-quality therapeutic reasoning in the case reports they publish.