Cardiac adaptations to patent ductus arteriosus ligation in preterm infants: a speckle-tracking study
Preoperatively, preterm infants with PDA had higher left ventricular global longitudinal strain (LVGLS), and lower right ventricular free wall strain (RVFWSL) than those without PDA. After PDA ligation, LVGLS and left atrial reservoir strain (LASr) initially decreased and then recovered within 24-48 h, while RVFWSL rapidly improved. Our findings indicate dynamic and different post-surgical cardiac adaptation in the right ventricle and left ventricle after PDA ligation.
Authors
- Toshihide Asou (ORCID: https://orcid.org/0000-0002-5358-9715)
- Takahiro Kemmotsu
- Yurika Furukawa
- Hirosato Aoki (ORCID: https://orcid.org/0000-0002-8558-7693)
- Tsuyoshi Tachibana
- Katsuaki Toyoshima (ORCID: https://orcid.org/0000-0002-7817-9907)
- Jun Shibasaki (ORCID: https://orcid.org/0000-0003-4986-4697)
- Takahiro Noguchi (ORCID: https://orcid.org/0009-0001-6300-3386)
- Gakuto Ujiie
- Satoshi Masutani (ORCID: https://orcid.org/0000-0002-1551-9089)
- Tomoyuki Shimokaze (ORCID: https://orcid.org/0000-0001-8490-475X)
- Motoyoshi Kawataki
- Yusuke Morita (ORCID: https://orcid.org/0000-0002-5850-3175)
- Naka Saito
- Tatsuto Shimizu
- Tomoko Saito (ORCID: https://orcid.org/0000-0001-7179-0765)
Institutions
- Kanagawa Children's Medical Center (JP)
- Social Insurance Saitama Chuo Hospital (JP)
- Saitama Medical University (JP)
Publication Details
- Journal
- Pediatric Research
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1038/s41390-025-04182-y
- Citations
- 3
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Japan Society for the Promotion of Science