Prenatal diagnosis and genetic assessment of fetuses with single umbilical artery using chromosomal microarray analysis: a seven-year single-center retrospective study
CMA markedly improved the identification of clinically relevant genetic alterations in fetuses presenting with a single umbilical artery, especially when the anomaly occurred in isolation. These findings highlight the value of CMA for uncovering the genetic contributors to SUA and advance the characterization of genotype-phenotype relationships in these cases.
Authors
- Chunnuan Chen (ORCID: https://orcid.org/0000-0002-8906-3184)
- Jia‐Ling Wu (ORCID: https://orcid.org/0000-0002-7785-9134)
- Xiaofang Ye
- Yue Chen (ORCID: https://orcid.org/0000-0001-9224-4165)
- Jianlong Zhuang
- Nan Huang
Institutions
- Fujian Medical University (CN)
- Quanzhou Normal University (CN)
- Fujian Women and Children Hospital (CN)
- Quzhou City People's Hospital (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1186/s12884-025-07886-5
- Citations
- 1
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Natural Science Foundation of Fujian Province
- Huaqiao University
- Science and Technology Bureau of Quanzhou