Unveiling the Molecular Landscape of <scp>MPO</scp> in Kikuchi's Disease: Protein Expression, <scp>mRNA</scp> Levels, and Genetic Polymorphisms
In Kikuchi's disease, both the protein and mRNA expression levels of MPO are elevated, and the high expression of mRNA is positively correlated with the protein expression levels. The polymorphism at the MPO-463 locus may be associated with the occurrence of Kikuchi's disease.
Authors
- MengNa Zhang
- Ma Yu (ORCID: https://orcid.org/0000-0002-1619-0481)
- Wensheng Li (ORCID: https://orcid.org/0000-0002-1172-3349)
- Yu Chang (ORCID: https://orcid.org/0000-0003-4774-1255)
- Chen Chang (ORCID: https://orcid.org/0009-0009-6043-0209)
Institutions
- Northwestern Polytechnical University (CN)
- Shanxi Medical University (CN)
- Shaanxi Provincial People's Hospital (CN)
- Affiliated Hospital of Shaanxi University of Chinese Medicine (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- International Journal of Laboratory Hematology
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1111/ijlh.14509
- Primary Topic
- Lymphadenopathy Diagnosis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shaanxi Province
- Yakult Bio-Science Foundation
- Key Research and Development Projects of Shaanxi Province