Early fibrinogen replacement based on shock index and lactate levels in massive postpartum hemorrhage: a retrospective cohort study.
Early fibrinogen replacement based on shock index and lactate levels appears feasible and beneficial in managing massive PPH. This approach was associated with improved hemostatic control, reduced ICU admissions, and fewer surgical interventions. Prospective studies are warranted to further assess this strategy's safety, efficacy, and cost-effectiveness.
Authors
- Ateş Karateke (ORCID: https://orcid.org/0000-0002-0199-6474)
- Selçuk Selçuk (ORCID: https://orcid.org/0000-0001-6436-4020)
- Mehmet Küçükbaş
- Eda GÜNER ÖZEN (ORCID: https://orcid.org/0000-0003-1102-9741)
- Mesut Polat (ORCID: https://orcid.org/0000-0003-0618-742X)
- Süleyman Özen (ORCID: https://orcid.org/0000-0002-4870-2840)
Institutions
- Istanbul Memorial Hospital (TR)
Publication Details
- Journal
- PubMed
- Published
- 2025-11-06
- DOI
- https://doi.org/10.2450/bloodtransfus.1044
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- İstanbul Medeniyet Üniversitesi