STUDY OF RED BLOOD CELL DISTRIBUTION WIDTH AND NEUTROPHIL-TO- LYMPHOCYTE RATIO IN PREDICTING ADVERSE OUTCOMES OF ACUTE KIDNEY INJURY IN HOSPITALISED PATIENTS

Acute kidney injury (AKI), formerly referred to as acute renal failure (ARF), signifies a rapid and frequently reversible decline in renal function, as assessed by glomerular filtration rate (GFR).(1,2) KIDGO defines acute kidney injury (AKI) as a rise in serum creatinine of 0.3 mg/dl or more (26.5 micromoles/L or more) within 48 hours, an increase in serum creatinine to 1.5 times or more of baseline within the preceding seven days, or urine output of less than 0.5 mL/kg/h for at least six hours. The predominant causes of acute kidney injury (AKI) are acute tubular necrosis (ATN) at 45%, prerenal disease at 21%, urinary tract obstruction at 10%, glomerulonephritis or vasculitis at 4%, acute interstitial nephritis (AIN) at 2%, and atheroemboli at 1%.