The Role of Echocardiographic Right Atrial Strain Parameters in Evaluating Atrial Fibrillation Recurrence in Patients Undergoing Atrial Fibrillation Ablation

<b>Background:</b> Atrial fibrillation (AF) recurrence following catheter ablation remains a significant clinical challenge despite technological advancements, with recurrence rates in the range of 20-40%. While left atrial parameters have been extensively studied as predictors of recurrence, the contribution of right atrial mechanical function has received limited attention. The hypothesis that the combined assessment of right and left atrial strain parameters may provide superior predictive value represents an important clinical question with potential implications for post-ablation risk stratification and follow-up strategies. <b>Methods:</b> This single-center, retrospective cohort study included 100 consecutive adult patients who underwent AF ablation between May 2022 and June 2024 with at least one-year follow-up. Patients were divided into two groups: those with recurrence (<i>n</i> = 13) and those without recurrence (<i>n</i> = 87). A comprehensive echocardiographic assessment, including the speckle-tracking strain analysis of both atria, was performed. <b>Results:</b> The median follow-up was 365 days [range: 150-912 days] in patients with recurrence. In the multivariable analysis, right ventricular diameter (OR: 0.74; 95% CI: 0.61-0.90; <i>p</i> = 0.001), left ventricular end-diastolic volume (OR: 1.04; 95% CI: 1.00-1.08; <i>p</i> = 0.022), and left ventricular global longitudinal strain rate (OR: 1.22; 95% CI: 1.05-1.40; <i>p</i> = 0.007) emerged as independent predictors of recurrence. <b>Conclusions:</b> The significant association of right atrial longitudinal reservoir strain with recurrence in univariable analysis, although not retained as an independent predictor in the multivariable model, suggests the importance of comprehensive cardiac assessment including right heart parameters in predicting AF recurrence.