Tuning the Magnetoelectric Stimulation Method to Enhance Cell Proliferation in PVDF-based Nanocomposites

A combination of materials such as a PVDF-based composite with 10 wt % CoFe2O4 nanoparticles and a method of ME stimulation of stem cells using a perpendicularly shifting low-frequency (0.3 Hz) magnetic field with a given amplitude are proposed. Optimal stimulation parameters—magnetic field strength, number of stimulations per day and duration—are systematically established to maximize the proliferation of multipotent mesenchymal stem cells up to 30% confirmed by WST-1 analysis.

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Publication Details

Journal
Nanobiotechnology Reports
Published
2025-04-01
DOI
https://doi.org/10.1134/s2635167624602559
Primary Topic
Advanced Sensor and Energy Harvesting Materials
Type
article
Field-Weighted Citation Impact
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article

Tuning the Magnetoelectric Stimulation Method to Enhance Cell Proliferation in PVDF-based Nanocomposites

Alexander S. Omelyanchik, Vitalii D. Salnikov, Petro Vorontsov, Valentina Antipova et al.
2 links
Nanobiotechnology Reports
Advanced Sensor and Energy Harvesting Materials
article

Tuning the Magnetoelectric Stimulation Method to Enhance Cell Proliferation in PVDF-based Nanocomposites

Alexander S. Omelyanchik, Vitalii D. Salnikov, Petro Vorontsov, Valentina Antipova, Valeria Rodionova, P. A. Ershov, Kateryna Levada, Alexander Ignatov, D. K. Turusheva
article en

Abstract

A combination of materials such as a PVDF-based composite with 10 wt % CoFe2O4 nanoparticles and a method of ME stimulation of stem cells using a perpendicularly shifting low-frequency (0.3 Hz) magnetic field with a given amplitude are proposed. Optimal stimulation parameters—magnetic field strength, number of stimulations per day and duration—are systematically established to maximize the proliferation of multipotent mesenchymal stem cells up to 30% confirmed by WST-1 analysis.

Nanobiotechnology ReportsVol. 20(2)
Immanuel Kant Baltic Federal University (RU)
Openalex Percentile: Top 84%
Advanced Sensor and Energy Harvesting Materials
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