Single cell sequencing deciphering the heterogeneous landscape of blastic plasmacytoid dendritic cell neoplasm with novel MYB-ZFAT fusion gene

The study indicates BPDCN's complexity with varied cellular origins and a significant role for MYB activation in its development. This research deepens our comprehension of BPDCN's pathogenesis and cell populations.

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Publication Details

Journal
Cancer Cell International
Published
2025-07-21
DOI
https://doi.org/10.1186/s12935-025-03899-4
Primary Topic
Cutaneous lymphoproliferative disorders research
Type
article
Field-Weighted Citation Impact
0.00

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article

Single cell sequencing deciphering the heterogeneous landscape of blastic plasmacytoid dendritic cell neoplasm with novel MYB-ZFAT fusion gene

Zhao Cheng, Kexin Zhao, Ruijuan Li, Weiyi Fang et al.
Cancer Cell International
Cutaneous lymphoproliferative disorders research
article

Single cell sequencing deciphering the heterogeneous landscape of blastic plasmacytoid dendritic cell neoplasm with novel MYB-ZFAT fusion gene

Zhao Cheng, Kexin Zhao, Ruijuan Li, Weiyi Fang, Wenyong Kuang, Zhang Ben-shan, Haixia Yang, Xianming Fu, Hongling Peng
article en

Abstract

The study indicates BPDCN's complexity with varied cellular origins and a significant role for MYB activation in its development. This research deepens our comprehension of BPDCN's pathogenesis and cell populations.

Cancer Cell InternationalVol. 25(1)
Central South University (CN), Second Xiangya Hospital of Central South University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Hunan Province
Life in Land
Openalex Percentile: Top 69%
Cutaneous lymphoproliferative disorders research
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