Innovative Use of a Virtual Ward in Managing Severe Neutropenia From Epstein-Barr Virus (EBV)-Associated Mononucleosis: A Case Report

Epstein-Barr virus (EBV)-associated infectious mononucleosis (IM) is a common condition worldwide; however, presenting with severe neutropenia is not something encountered very often. We report such a rare case, where a 19-year-old male patient presented with typical features of mononucleosis and a neutrophil count as low as 0.2 × 10⁹/L. Diagnostic investigations confirmed an EBV infection, while ruling out any hematological or vascular disorder. To reduce the risk of nosocomial infections, it was decided to monitor the patient by remote electronic devices from the comfort of his home under the care of a virtual ward, aiming for full recovery over time. He received his intravenous (IV) antibiotics at home, and alternate-day blood tests showed a gradual and spontaneous rise in his neutrophil count back to baseline levels without any complications. This case highlights the promising role of virtual wards in reducing hospitalization while ensuring patient safety and effective management, particularly when prolonged hospital stay poses added infection risks.