Prediction of 1-Year Major Adverse Cardiovascular Events in Chronic Limb Threatening Ischemia
The BEST-CLI MACE model predicts 1-year MACE in CLTI, is not influenced by mode of revascularization, and highlights the importance of statin therapy. Further work is needed to determine if this model may be helpful in guiding therapeutic decision-making in CLTI patients.
Authors
- Joshua A. Beckman (ORCID: https://orcid.org/0000-0001-8332-8439)
- Manesh R. Patel (ORCID: https://orcid.org/0000-0002-2393-0855)
- Naomi M. Hamburg (ORCID: https://orcid.org/0000-0001-5504-5589)
- Gheorghe D. Doros (ORCID: https://orcid.org/0000-0001-5524-4721)
- Matthew T. Menard (ORCID: https://orcid.org/0000-0003-2470-7978)
- Alik Farber (ORCID: https://orcid.org/0000-0001-7231-4189)
- W Schuyler Jones
- E. Hope Weissler (ORCID: https://orcid.org/0000-0002-8442-6150)
- Kenneth Rosenfield
- Michael R. Jaff (ORCID: https://orcid.org/0000-0002-3772-5887)
- Sreekanth Vemulapalli (ORCID: https://orcid.org/0000-0003-1599-2957)
- Shuang Li (ORCID: https://orcid.org/0000-0002-0550-8722)
- Michael B. Strong (ORCID: https://orcid.org/0000-0001-9144-6806)
- Sean M. O’Brien
Institutions
- Boston University (US)
- Brigham and Women's Hospital (US)
- Boston Medical Center (US)
- Harvard University (US)
- Duke University (US)
- Massachusetts General Hospital (US)
- Clinical Research Institute (US)
- Southwestern Medical Center (US)
- Duke Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- JACC Advances
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1016/j.jacadv.2025.101959
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Novo Nordisk Fonden
- National Institutes of Health