Differential Methylation Patterns Predict HBsAg Seroconversion in Hepatitis B Virus Reactivation Patients
This study identifies hypomethylation of immune genes suggesting enhanced immune response and viral clearance in SC. Conversely, nCHBV and NSC consistently exhibited hypomethylation of LAG3 and TOX, contributing to immune exhaustion.
Authors
- Shahana Parveen (ORCID: https://orcid.org/0000-0001-9239-1691)
- Ankur Jindal (ORCID: https://orcid.org/0000-0001-5582-7759)
- Anoushka Saxena
- Manoj Kumar (ORCID: https://orcid.org/0000-0003-3448-8334)
- Shiv Kumar Sarin (ORCID: https://orcid.org/0000-0002-0544-5610)
- Jayesh Kumar Sevak (ORCID: https://orcid.org/0000-0003-2725-5516)
- Mojahidul Islam (ORCID: https://orcid.org/0000-0001-7219-9686)
- Nirupma Trehanpati (ORCID: https://orcid.org/0000-0002-6109-0033)
- Syed Naqui Kazim (ORCID: https://orcid.org/0000-0002-4248-0511)
- Gayatri Ramakrishna (ORCID: https://orcid.org/0000-0003-4345-294X)
- Gayantika Verma (ORCID: https://orcid.org/0009-0004-2314-1516)
- Preedia Babu E
Institutions
- Institute of Liver and Biliary Sciences (IN)
- Jamia Millia Islamia (IN)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1080/08820139.2025.2532630
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00