Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous RE104

Single SC doses of RE104 resulted in a psychoactive experience and a favorable safety profile similar to psilocybin but with a shorter duration of psychoactive effect (3 to 4 hours). Results suggest a potential for therapeutic effect, warranting further study.

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Publication Details

Journal
Journal of Clinical Psychopharmacology
Published
2025-07-21
DOI
https://doi.org/10.1097/jcp.0000000000002047
Primary Topic
Psychedelics and Drug Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous RE104

Nathan Bryson, Guy Ludbrook, Matthew W. Johnson, Glynn Morrish et al.
1 links
Journal of Clinical Psychopharmacology
Psychedelics and Drug Studies
article

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous RE104

Nathan Bryson, Guy Ludbrook, Matthew W. Johnson, Glynn Morrish, Brendan Taylor, Jasna Hocevar‐Trnka, Mark H. Pollack, Joe Hirman, Robert Alexander
article en

Abstract

Single SC doses of RE104 resulted in a psychoactive experience and a favorable safety profile similar to psilocybin but with a shorter duration of psychoactive effect (3 to 4 hours). Results suggest a potential for therapeutic effect, warranting further study.

Journal of Clinical PsychopharmacologyVol. 45(5)
Royal Adelaide Hospital (AU), Sheppard and Enoch Pratt Hospital (US), Morristown High School (US), Statistical Research (United States) (US), The University of Adelaide (AU)
Openalex Percentile: Top 75%
Psychedelics and Drug Studies
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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous RE104 — Nathan Bryson, Guy Ludbrook, et al. · Journal of Clinical Psychopharmacology (2025) | TGRS Research Map | TGRS