Pectoral muscle area index is an independent protective factor for mortality in sepsis patients: a retrospective observational study
In this study, 88 patients survived, whereas 46 did not survive at the 28-day mark. Body mass index (BMI) (<i>P</i> = 0.044), pectoral muscle area (<i>P</i> = 0.005), pectoral muscle density (<i>P</i> = 0.008), and pectoral muscle area index (<i>P</i> = 0.003) significantly differed between patients who survived and those who did not survive. BMI was positively correlated with pectoral muscle area (<i>r</i> = 0.516, <i>P</i> < 0.001) and index (<i>r</i> = 0.560, <i>P</i> < 0.001). Acute Physiology and Chronic Health Evaluation II score (hazard ratio (HR) = 1.119, <i>P</i> < 0.001) constituted an independent risk factor for 28-day mortality, whereas the pectoral muscle area index (HR, 0.847; <i>P</i> = 0.027) was a protective factor for 28-day mortality in patients with sepsis. The pectoral muscle area index was associated with a reduced risk of early mortality in patients with sepsis.
Authors
- Yongchang Sun (ORCID: https://orcid.org/0000-0003-3281-8854)
- Xin Li (ORCID: https://orcid.org/0000-0002-1013-3566)
- Meijiao Li (ORCID: https://orcid.org/0000-0002-0588-594X)
- Qingtao Zhou (ORCID: https://orcid.org/0000-0002-2661-9691)
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-07-21
- DOI
- https://doi.org/10.7717/peerj.19689
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking University Third Hospital