Anticancer Effect of Nature-Inspired Indolizine-Based Pentathiepines in 2D and 3D Cellular Model
Our findings reveal that four PTEs bearing hydrophilic, hydrogen-bonding functional groups, particularly the two inspired by natural analogs, exhibited the most potent anticancer activity.
Authors
- Siva Sankar Murthy Bandaru
- Michel Riva
- Marzia Bruna Gariboldi (ORCID: https://orcid.org/0000-0002-5683-0885)
- Carola Schulzke (ORCID: https://orcid.org/0000-0002-7530-539X)
- Emanuela Marras (ORCID: https://orcid.org/0000-0002-9363-1201)
- Roberto Tallarita
- Lukas M. Jacobsen
- Federica Randisi
- Giulia Modoni
- Johannes Fimmen
Institutions
- University of Insubria (IT)
- Universität Greifswald (DE)
Publication Details
- Journal
- Cancers
- Published
- 2025-07-19
- DOI
- https://doi.org/10.3390/cancers17142393
- Citations
- 1
- Primary Topic
- Synthesis and Reactivity of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.94