Evaluating the impact of population-based and cohort-based models in cost-effectiveness analysis: a case study of pneumococcal conjugate vaccines in infants in Germany

This analysis highlights the importance of accurately identifying the relevant population when conducting CEAs of vaccines. This is particularly crucial when a vaccine produces indirect effects in individuals who are not directly vaccinated, as this otherwise leads to an underestimation of cost-effectiveness.

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Publication Details

Journal
Journal of Medical Economics
Published
2025-07-21
DOI
https://doi.org/10.1080/13696998.2025.2536430
Primary Topic
Pharmaceutical studies and practices
Type
article
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article

Evaluating the impact of population-based and cohort-based models in cost-effectiveness analysis: a case study of pneumococcal conjugate vaccines in infants in Germany

Johnna Perdrizet, Christian Theilacker, Julia Schiffner-Rohe, Dominik Schröder et al.
Journal of Medical Economics
Pharmaceutical studies and practices
article

Evaluating the impact of population-based and cohort-based models in cost-effectiveness analysis: a case study of pneumococcal conjugate vaccines in infants in Germany

Johnna Perdrizet, Christian Theilacker, Julia Schiffner-Rohe, Dominik Schröder, An Ta, Maren Laurenz, Felicitas Kühne, Christof von Eiff, Aleksandar Ilic
article en

Abstract

This analysis highlights the importance of accurately identifying the relevant population when conducting CEAs of vaccines. This is particularly crucial when a vaccine produces indirect effects in individuals who are not directly vaccinated, as this otherwise leads to an underestimation of cost-effectiveness.

Journal of Medical EconomicsVol. 28(1)
Pfizer (United Kingdom) (GB), Pfizer (Germany) (DE), Evidence (Italy) (IT), Pfizer (Canada) (CA), Cytel (United States) (US)
Zero hunger
Openalex Percentile: Top 75%
Pharmaceutical studies and practices
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Evaluating the impact of population-based and cohort-based models in cost-effectiveness analysis: a case study of pneumococcal conjugate vaccines in infants in Germany — Johnna Perdrizet, Christian Theilacker, et al. · Journal of Medical Economics (2025) | TGRS Research Map | TGRS