clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries

clonevdjseq offers a comprehensive and scalable solution for the processing and analysis of large monoclonal and oligoclonal VDJ datasets. Its modular design, dynamic pipeline, and robust database integration facilitate efficient data management and analysis. The platform is publicly available and aims to support the research community by providing an accessible and flexible tool for archiving and dissemination of BCR sequences from hybridomas, with applicability for other applications such as TCR sequences from single-cell T cell populations.

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Publication Details

Journal
BMC Bioinformatics
Published
2025-07-21
DOI
https://doi.org/10.1186/s12859-025-06107-2
Citations
3
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
2.42

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article

clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries

Karl D. Murray, Samuel S. Hunter, Lutz Froenicke, Keith G. Mitchell et al.
3 citations
BMC Bioinformatics
Single-cell and spatial transcriptomics
2.42
article

clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries

Karl D. Murray, Samuel S. Hunter, Lutz Froenicke, Keith G. Mitchell, James S. Trimmer, Matthew L. Settles
article en
3 citations

Abstract

clonevdjseq offers a comprehensive and scalable solution for the processing and analysis of large monoclonal and oligoclonal VDJ datasets. Its modular design, dynamic pipeline, and robust database integration facilitate efficient data management and analysis. The platform is publicly available and aims to support the research community by providing an accessible and flexible tool for archiving and dissemination of BCR sequences from hybridomas, with applicability for other applications such as TCR sequences from single-cell T cell populations.

BMC BioinformaticsVol. 26(1)
University of California, Davis (US)
National Institutes of Health
Openalex Percentile: Top 11%
Single-cell and spatial transcriptomics
2.42
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clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries — Karl D. Murray, Samuel S. Hunter, et al. · BMC Bioinformatics (2025) | TGRS Research Map | TGRS