Investigating the effects of age and conditioning stimulation intensity on SMA–M1 connectivity in younger, middle-aged, and older adults
Age-related declines in bilateral motor functioning was found in older, but not middle-aged adults. The bilateral motor functioning of middle-aged adults is more young-like than old-like. The lack of conclusive age- and intensity-related differences in SMA-M1 connectivity, and lack of conclusive association with bilateral motor performance, might be due to high inter-individual variability in SMA-M1 connectivity. Potential factors contributing to this variability include SMA and M1 morphometry, the structural connectivity between these regions, and the localisation of SMA.
Authors
- Rohan Puri (ORCID: https://orcid.org/0000-0002-0231-1369)
- Jane Tan (ORCID: https://orcid.org/0000-0002-0826-5391)
- Merrilee Needham (ORCID: https://orcid.org/0000-0001-6591-1444)
- Shivani Radia
- Michelle Marneweck (ORCID: https://orcid.org/0000-0002-3953-5956)
- Ann‐Maree Vallence (ORCID: https://orcid.org/0000-0001-9190-6366)
- Grant Rowe (ORCID: https://orcid.org/0000-0002-6980-0511)
Institutions
- University of Tasmania (AU)
- Murdoch University (AU)
- University of Oregon (US)
- Fiona Stanley Hospital (AU)
- North Metropolitan Health Service (AU)
- Perron Institute for Neurological and Translational Science (AU)
- Avenir Health (US)
- South Metropolitan Health Service (AU)
Publication Details
- Journal
- European Journal of Applied Physiology
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1007/s00421-025-05904-0
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Murdoch University
- Fiona Wood Foundation
- Australian Research Council