Cost-effectiveness analysis of cadonilimab plus chemotherapy as a first-line treatment option in HER-2-negative advanced gastric cancer

The addition of cadonilimab to standard chemotherapy for first line treatment of HER-2-negative advanced gastric cancer may not be considered a cost-effective option compared to chemotherapy alone. However, for the subgroup of patients with PD-L1CPS ≥ 5, the ICER was 26,813.44 USD per QALY, indicating that this treatment approach could potentially be deemed cost-effective in China.

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Publication Details

Journal
Frontiers in Public Health
Published
2025-07-21
DOI
https://doi.org/10.3389/fpubh.2025.1644176
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Cost-effectiveness analysis of cadonilimab plus chemotherapy as a first-line treatment option in HER-2-negative advanced gastric cancer

Zhiwei Zheng, Qingsheng Yang, Longfeng Zhang
Frontiers in Public Health
Gastric Cancer Management and Outcomes
article

Cost-effectiveness analysis of cadonilimab plus chemotherapy as a first-line treatment option in HER-2-negative advanced gastric cancer

Zhiwei Zheng, Qingsheng Yang, Longfeng Zhang
article en

Abstract

The addition of cadonilimab to standard chemotherapy for first line treatment of HER-2-negative advanced gastric cancer may not be considered a cost-effective option compared to chemotherapy alone. However, for the subgroup of patients with PD-L1CPS ≥ 5, the ICER was 26,813.44 USD per QALY, indicating that this treatment approach could potentially be deemed cost-effective in China.

Frontiers in Public HealthVol. 13
Fujian Medical University (CN), Shantou University (CN), Cancer Hospital of Shantou University Medical College (CN), Shantou Central Hospital (CN), Fujian Provincial Cancer Hospital (CN)
Openalex Percentile: Top 72%
Gastric Cancer Management and Outcomes
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