JMJD8 overexpression in breast cancer: implications for diagnosis, prognosis, and immune microenvironment interactions
The elevated expression of JMJD8 in breast cancer tissues is indicative of its involvement in the progression of the disease and its association with immune cell infiltration patterns. Our findings support the hypothesis that JMJD8 could serve as a prognostic biomarker, reflecting the immunosuppressive characteristics of the tumor microenvironment and aiding in the development of targeted therapeutic strategies for breast cancer management.
Authors
- Tianyi Xi
- Jiwei Cao (ORCID: https://orcid.org/0000-0002-3029-8819)
- Wen Lü (ORCID: https://orcid.org/0000-0002-8849-8100)
- Sentai Wang
- Chenlei Zhu
- Guorong Yang (ORCID: https://orcid.org/0009-0001-7444-921X)
Institutions
- Suzhou Municipal Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-07-21
- DOI
- https://doi.org/10.3389/fonc.2025.1536278
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Suzhou Municipal Health Commission
- Science and Technology Program of Suzhou