Research Progress in the Synthesis of Six-Membered and Medium-Sized Rings via Intramolecular Olefin-Carbonyl Metathesis Reaction

烯–羰复分解反应作为碳–碳键构建的重要合成方法，该反应的成功实施高度依赖于催化剂的开发，经过数十年的发展，目前已具有较为完善的催化体系。分子内的烯–羰复分解反应为构建碳环或杂环化合物提供了高效途径，在材料和复杂分子合成中具有良好的利用价值。本文主要介绍了烯–羰复分解反应在合成六元环、中环化合物的应用，并对相关催化剂和反应机理进行介绍。The alkene-carbonyl metathesis reaction serves as an important synthetic method for carbon-carbon bond formation, and its successful implementation heavily relies on the development of catalysts. After decades of progress, a relatively well-established catalytic system has been achieved. Intramolecular alkene-carbonyl metathesis provides an efficient route for constructing carbocyclic or heterocyclic compounds, demonstrating significant value in materials science and complex molecule synthesis. This article primarily focuses on the application of alkene-carbonyl metathesis in the synthesis of six-membered and medium-sized rings, along with an introduction to relevant catalysts and reaction mechanisms.