A Rare Occurrence of a Metastatic Deposit of Meningioma in a Cervical Lymph Node

Meningioma is a common primary central nervous system (CNS) tumour, in which recurrences and local invasion can occur depending on the CNS World Health Organisation (WHO) grade. Extracranial spread of meningioma is rare and mostly includes metastasis to liver, lung, mediastinum and bone. Cervical lymph node involvement is extremely rare and only a few cases have been reported. This is a case of a 57-year-old man, with a diagnosis of CNS WHO grade 2 meningioma who presented with cervical lymph node (level II) enlargement. Microscopically whorls and sheets of cells resembling a meningioma were observed with diffuse EMA positivity. Although it is a rare occurrence, the possibility of metastatic meningioma should be considered in the differential diagnosis of cases of cervical lymph node metastasis, in patients with primary meningioma. Extracranial spread of meningioma carries a relatively poor prognosis. Early diagnosis is important as the excision of primary/secondary disease followed radiotherapy is the currently recommended treatment.

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Publication Details

Journal
Journal of Diagnostic Pathology
Published
2025-07-21
DOI
https://doi.org/10.4038/jdp.v19i1.7863
Primary Topic
Meningioma and schwannoma management
Type
article
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article

A Rare Occurrence of a Metastatic Deposit of Meningioma in a Cervical Lymph Node

Sarah Constantine, K. V. Chathurika Wijegunarathna
Journal of Diagnostic Pathology
Meningioma and schwannoma management
article

A Rare Occurrence of a Metastatic Deposit of Meningioma in a Cervical Lymph Node

Sarah Constantine, K. V. Chathurika Wijegunarathna
article en

Abstract

Meningioma is a common primary central nervous system (CNS) tumour, in which recurrences and local invasion can occur depending on the CNS World Health Organisation (WHO) grade. Extracranial spread of meningioma is rare and mostly includes metastasis to liver, lung, mediastinum and bone. Cervical lymph node involvement is extremely rare and only a few cases have been reported. This is a case of a 57-year-old man, with a diagnosis of CNS WHO grade 2 meningioma who presented with cervical lymph node (level II) enlargement. Microscopically whorls and sheets of cells resembling a meningioma were observed with diffuse EMA positivity. Although it is a rare occurrence, the possibility of metastatic meningioma should be considered in the differential diagnosis of cases of cervical lymph node metastasis, in patients with primary meningioma. Extracranial spread of meningioma carries a relatively poor prognosis. Early diagnosis is important as the excision of primary/secondary disease followed radiotherapy is the currently recommended treatment.

Journal of Diagnostic PathologyVol. 19(1)
National Hospital of Sri Lanka (LK)
Openalex Percentile: Top 75%
Meningioma and schwannoma management
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A Rare Occurrence of a Metastatic Deposit of Meningioma in a Cervical Lymph Node — Sarah Constantine, K. V. Chathurika Wijegunarathna · Journal of Diagnostic Pathology (2025) | TGRS Research Map | TGRS