Case Report: Carotid cavernous fistula presenting as red eye: case illustration and comprehensive review

Carotid cavernous fistula (CCF) is a pathological condition where an abnormal connection forms between the carotid artery and the cavernous sinus. This condition can lead to a variety of ocular and neurological symptoms, often making it difficult to diagnose, especially when patients present with common ocular complaints such as red eye, which is often misdiagnosed as conjunctivitis. The subtle and diverse symptoms of CCF can lead to misdiagnosis, delaying appropriate treatment. This article reports a case of CCF that initially presented with red eye and proptosis, leading to an ophthalmology referral. By comparing pre- and postoperative ocular photographs, the article provides a detailed review of the ophthalmic features, classification, diagnostic methods, and treatment options for CCF. The aim is to enhance clinicians' understanding of this condition, improve diagnostic accuracy at initial presentation, and promote timely and effective treatment.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-07-21
DOI
https://doi.org/10.3389/fmed.2025.1613326
Primary Topic
Vascular Malformations Diagnosis and Treatment
Type
article
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article

Case Report: Carotid cavernous fistula presenting as red eye: case illustration and comprehensive review

Qi‐Bin Xu, W. Y. Sheng
Frontiers in Medicine
Vascular Malformations Diagnosis and Treatment
article

Case Report: Carotid cavernous fistula presenting as red eye: case illustration and comprehensive review

Qi‐Bin Xu, W. Y. Sheng
article en

Abstract

Carotid cavernous fistula (CCF) is a pathological condition where an abnormal connection forms between the carotid artery and the cavernous sinus. This condition can lead to a variety of ocular and neurological symptoms, often making it difficult to diagnose, especially when patients present with common ocular complaints such as red eye, which is often misdiagnosed as conjunctivitis. The subtle and diverse symptoms of CCF can lead to misdiagnosis, delaying appropriate treatment. This article reports a case of CCF that initially presented with red eye and proptosis, leading to an ophthalmology referral. By comparing pre- and postoperative ocular photographs, the article provides a detailed review of the ophthalmic features, classification, diagnostic methods, and treatment options for CCF. The aim is to enhance clinicians' understanding of this condition, improve diagnostic accuracy at initial presentation, and promote timely and effective treatment.

Frontiers in MedicineVol. 12
Hangzhou Red Cross Hospital (CN)
Openalex Percentile: Top 73%
Vascular Malformations Diagnosis and Treatment
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Case Report: Carotid cavernous fistula presenting as red eye: case illustration and comprehensive review — Qi‐Bin Xu, W. Y. Sheng · Frontiers in Medicine (2025) | TGRS Research Map | TGRS