Case Report: Rare diffuse giant cell tumor of the tendon sheath in the cervical facet joint

Giant Cell Tumor of the Tendon Sheath (GCTTS) is a rare neoplasm that can exhibit local aggressiveness but is generally benign. GCTTS is commonly classified into two subtypes: localized and diffuse, and rarely affects the axial skeleton. Diagnosing GCTTS in the spine is challenging, and it is associated with localized pain and neurological symptoms. Surgical resection is now the preferred treatment, though recurrence rates remain high. This report describes an exceptionally rare case of rapidly progressive and extensively invasive diffuse GCTTS affecting the lateral joints, surrounding vasculature, and nerves of the cervical spine. We also review the clinical presentation, imaging characteristics, and therapeutic outcomes of spinal GCTTS to enhance understanding and awareness of this rare pathology.

Authors

Institutions

Publication Details

Journal
Frontiers in Oncology
Published
2025-07-21
DOI
https://doi.org/10.3389/fonc.2025.1555098
Primary Topic
Musculoskeletal synovial abnormalities and treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Case Report: Rare diffuse giant cell tumor of the tendon sheath in the cervical facet joint

Chongxi Xu, Yong‐Liang Jiang, Junpeng Ma, T. Luo
Frontiers in Oncology
Musculoskeletal synovial abnormalities and treatments
article

Case Report: Rare diffuse giant cell tumor of the tendon sheath in the cervical facet joint

Chongxi Xu, Yong‐Liang Jiang, Junpeng Ma, T. Luo
article en

Abstract

Giant Cell Tumor of the Tendon Sheath (GCTTS) is a rare neoplasm that can exhibit local aggressiveness but is generally benign. GCTTS is commonly classified into two subtypes: localized and diffuse, and rarely affects the axial skeleton. Diagnosing GCTTS in the spine is challenging, and it is associated with localized pain and neurological symptoms. Surgical resection is now the preferred treatment, though recurrence rates remain high. This report describes an exceptionally rare case of rapidly progressive and extensively invasive diffuse GCTTS affecting the lateral joints, surrounding vasculature, and nerves of the cervical spine. We also review the clinical presentation, imaging characteristics, and therapeutic outcomes of spinal GCTTS to enhance understanding and awareness of this rare pathology.

Frontiers in OncologyVol. 15
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Good health and well-being
Openalex Percentile: Top 72%
Musculoskeletal synovial abnormalities and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.