Osteocalcin deficiency attenuates neointima formation after vascular injury in rat
OCN participates in the pathological processes of vascular neointima formation and promotes inflammatory response of VSMC to vascular injury, but deletion of OCN does not affect vascular integrity under physiological condition, suggesting that OCN may provide new insights into the mechanism of intima hyperplasia.
Authors
- Si Jin (ORCID: https://orcid.org/0000-0003-0727-6715)
- Huirong Liu (ORCID: https://orcid.org/0009-0004-0974-8311)
- Ming Yi (ORCID: https://orcid.org/0000-0001-9904-1651)
- Jing Li (ORCID: https://orcid.org/0000-0003-3673-3567)
- Danni Li (ORCID: https://orcid.org/0000-0002-0608-2831)
- Jinghao Sun
Institutions
- Capital Medical University (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1186/s12872-025-05000-3
- Citations
- 1
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Natural Science Foundation of China