Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

PAD patients show differences in the expression of membrane-bound and soluble immune checkpoints. Some of these differences might be caused by prolonged immune activation, although immune exhaustion markers did not always overlap.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-07-21
DOI
https://doi.org/10.3389/fimmu.2025.1568431
Primary Topic
Atherosclerosis and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

Ashok Kumar Kumawat, Rosanne D. Reitsema, Hans Hjelmqvist, Seta Kurt et al.
Frontiers in Immunology
Atherosclerosis and Cardiovascular Diseases
article

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

Ashok Kumar Kumawat, Rosanne D. Reitsema, Hans Hjelmqvist, Seta Kurt, Mats Dreifaldt, Ignacio Rangel, Allan Sirsjö
article en

Abstract

PAD patients show differences in the expression of membrane-bound and soluble immune checkpoints. Some of these differences might be caused by prolonged immune activation, although immune exhaustion markers did not always overlap.

Frontiers in ImmunologyVol. 16
Örebro University (SE), Örebro County Council (SE), Örebro University Hospital (SE)
Openalex Percentile: Top 81%
Atherosclerosis and Cardiovascular Diseases
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