Analysis of immune characteristics and inflammatory mechanisms in COPD patients: a multi-layered study combining bulk and single-cell transcriptome analysis and machine learning
This study reveals significantly enriched biological processes and pathways in COPD patients, identifies multiple inflammatory-related COPD feature genes, and finds that cinnamaldehyde may have potential therapeutic effects on inflammatory subtypes of COPD.
Authors
- Feipeng Li (ORCID: https://orcid.org/0000-0002-7114-9617)
- Caiming Chen (ORCID: https://orcid.org/0000-0002-8021-6842)
- Zheng Li (ORCID: https://orcid.org/0000-0002-0433-6842)
- Yongfeng Zhu (ORCID: https://orcid.org/0000-0003-0679-7551)
- Changjin Wei
Institutions
- Riverside Hospital of Guangxi Zhuang Autonomous Region (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-07-21
- DOI
- https://doi.org/10.3389/fmed.2025.1592802
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52