Exploring the predictive “psycho-biomarkers” for checkpoint immunotherapy in cancer
This study suggests that depression-related genetic traits could serve as biomarkers for ICIs therapy response, tumor mutations, and immune system alterations. Our findings offer insights into personalized therapeutic strategies for early intervention and prognosis in specific cancer types.
Authors
- Yuqi Liang (ORCID: https://orcid.org/0000-0002-7481-116X)
- Yan Dai (ORCID: https://orcid.org/0000-0001-5890-8087)
- Junfeng Huang (ORCID: https://orcid.org/0000-0003-0984-9505)
- Yingchao Wu (ORCID: https://orcid.org/0000-0002-4810-0399)
- Liushan Chen (ORCID: https://orcid.org/0000-0003-0414-4987)
- Jieting Chen
- Rui‐Hua Xu (ORCID: https://orcid.org/0000-0001-9771-8534)
- Xi Xiao (ORCID: https://orcid.org/0009-0000-0931-6982)
- Qian Zuo
- Qianjun Chen (ORCID: https://orcid.org/0000-0001-6761-7740)
- Rutao Cui
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine (CN)
- Traditional Chinese Medicine Bureau of Guangdong Province (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-21
- DOI
- https://doi.org/10.3389/fimmu.2025.1590670
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Guangzhou University of Chinese Medicine
- Guangzhou University
- Guangdong Provincial Key Laboratory for Translational Cancer Research of Chinese Medicine, Guangzhou University of Chinese Medicine
- Guangzhou Municipal Science and Technology Project