PROSPECTIVE EVALUATION OF SERUM VITAMIN D LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS AND CORRELATION WITH GLYCEMIC CONTROL

Background: Type 2 Diabetes Mellitus (T2DM) is a growing global health concern. Recent evidence suggests a potential link between Vitamin D deficiency and poor glycemic control. This study aimed to evaluate serum Vitamin D levels in T2DM patients and analyze their correlation with glycemic parameters. Methods: This prospective observational study was conducted in the Department of Biochemistry, FH Medical College, Agra over 12 months. A total of 150 diagnosed T2DM patients were included. Serum 25(OH) Vitamin D and glycemic parameters (HbA1c, Fasting Blood Glucose [FBG], Postprandial Blood Glucose [PPBG]) were measured and analyzed. Results: Vitamin D deficiency (<20 ng/mL) was observed in 68% of patients. A statistically significant inverse correlation was found between serum Vitamin D levels and HbA1c (r = –0.42, p < 0.01). Similar trends were seen with FBG and PPBG. Conclusion: Vitamin D deficiency is highly prevalent in T2DM patients and is significantly associated with poor glycemic control. Screening and supplementation of Vitamin D may serve as an adjunct in the management of T2DM.