Lactobacilli-based postbiotic differentially affects chicken macrophage-like HD11 cells depending on stimulatory lipopolysaccharide dosage
Our results showed that Post had a pro-inflammatory effect, which was exacerbated in the presence of a 300 but not 3 ng/ml LPS. Furthermore, the dose of LPS affected the sensitivity of the cells to Post. Dose-response studies should be performed when investigating the effects of dietary compounds on inflammation in chicken macrophages.
Authors
- Fany Blanc (ORCID: https://orcid.org/0000-0003-2366-9826)
- J. van Baal
- A. Lammers (ORCID: https://orcid.org/0000-0002-1876-9630)
- Samuel C G Jansseune (ORCID: https://orcid.org/0000-0003-1634-1769)
Institutions
- AgroParisTech (FR)
- Université Paris-Saclay (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Wageningen University & Research (NL)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1186/s12917-025-04902-w
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Association Nationale de la Recherche et de la Technologie
- Wageningen University and Research