A causal relationship between circulating immune cells, plasma metabolites, and pulmonary diseases: a mediated Mendelian randomization study

We clarify the importance of the potential mechanisms pertaining to immune cells, metabolites, and pulmonary diseases, highlighting the complex interactions among these factors. This understanding may assist in the diagnosis and treatment of patients with pulmonary diseases.

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Publication Details

Journal
Journal of Genetic Engineering and Biotechnology
Published
2025-07-21
DOI
https://doi.org/10.1016/j.jgeb.2025.100537
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
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article

A causal relationship between circulating immune cells, plasma metabolites, and pulmonary diseases: a mediated Mendelian randomization study

Chao Lv, Longxiang Xie, Abualgasim Elgaili Abdalla, Chenyi Zhao et al.
1 links
Journal of Genetic Engineering and Biotechnology
Chronic Obstructive Pulmonary Disease (COPD) Research
article

A causal relationship between circulating immune cells, plasma metabolites, and pulmonary diseases: a mediated Mendelian randomization study

Chao Lv, Longxiang Xie, Abualgasim Elgaili Abdalla, Chenyi Zhao, Yuhan Li, Xin Song, Guirong Wang, Dan Yang, Tingyu Shi
article en

Abstract

We clarify the importance of the potential mechanisms pertaining to immune cells, metabolites, and pulmonary diseases, highlighting the complex interactions among these factors. This understanding may assist in the diagnosis and treatment of patients with pulmonary diseases.

Journal of Genetic Engineering and BiotechnologyVol. 23(3)
Henan University (CN), Jouf University (SA), Henan University Huaihe Hospital and Huaihe Clinical Institute (CN), Hubei University for Nationalities (CN), Beijing Chest Hospital (CN), Fourth Hospital of Inner Mongolia (CN)
Openalex Percentile: Top 72%
Chronic Obstructive Pulmonary Disease (COPD) Research
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A causal relationship between circulating immune cells, plasma metabolites, and pulmonary diseases: a mediated Mendelian randomization study — Chao Lv, Longxiang Xie, et al. · Journal of Genetic Engineering and Biotechnology (2025) | TGRS Research Map | TGRS