Exploring connectivity and volume alterations in the Pulvinar’s subnuclei: insights into the neuropathological role in obsessive-compulsive disorder (OCD)

Our study identified functional connectivity alterations within specific subnuclei, including the left and right PuA, and the left PuL, alongside GMV changes in the left PuA. These observations suggest that these distinct regions of the pulvinar may contribute to the pathophysiology of OCD through differences in both functional connectivity and GMV compared to healthy controls.

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Publication Details

Journal
Psychological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1017/s0033291725100998
Primary Topic
Obsessive-Compulsive Spectrum Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring connectivity and volume alterations in the Pulvinar’s subnuclei: insights into the neuropathological role in obsessive-compulsive disorder (OCD)

Tuncay Çolak, Sevilay Ayyıldız, Behçet Ayyıldız, Kathrin Koch et al.
Psychological Medicine
Obsessive-Compulsive Spectrum Disorders
article

Exploring connectivity and volume alterations in the Pulvinar’s subnuclei: insights into the neuropathological role in obsessive-compulsive disorder (OCD)

Tuncay Çolak, Sevilay Ayyıldız, Behçet Ayyıldız, Kathrin Koch, Daniela Rodriguez-Manrique
article en

Abstract

Our study identified functional connectivity alterations within specific subnuclei, including the left and right PuA, and the left PuL, alongside GMV changes in the left PuA. These observations suggest that these distinct regions of the pulvinar may contribute to the pathophysiology of OCD through differences in both functional connectivity and GMV compared to healthy controls.

Psychological MedicineVol. 55
Munich School of Philosophy (DE), Cognitive Neuroimaging Lab (FR), Kocaeli Üniversitesi (TR), Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 75%
Obsessive-Compulsive Spectrum Disorders
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