Mucosal barrier injury as an independent risk factor for laboratory-confirmed bloodstream infection in patients with hematological malignancies: a real-world study
MBI is an independent risk factor for BSI in HM patients, highlighting the need for targeted mucosal protection strategies. MBI-LCBI pathogens primarily originate from the gut/oral flora, and are distinct from catheter-related infections. Carbapenems are recommended for empirical therapy, yet resistance surveillance remains essential.
Authors
- Xianwen Dai (ORCID: https://orcid.org/0000-0001-7765-7674)
- Yingqi Pi
- Yanrong Guo (ORCID: https://orcid.org/0000-0001-6949-4879)
- Yixian Wu (ORCID: https://orcid.org/0009-0002-2613-3760)
- Xiuqin Ren
- Mingming Chen (ORCID: https://orcid.org/0000-0003-2059-6342)
- Mei Liu (ORCID: https://orcid.org/0000-0003-0445-941X)
- Xinyi Zhang (ORCID: https://orcid.org/0000-0002-3158-4438)
- Zhaofan Luo
- Xiaoying Xie
- Xi Jiang (ORCID: https://orcid.org/0000-0003-0615-4476)
Institutions
- Sun Yat-sen University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1186/s40001-025-02913-9
- Citations
- 1
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Shenzhen Science and Technology Innovation Program
- Basic and Applied Basic Research Foundation of Guangdong Province