Circulating miRNAs correlate with clinical evaluation of activity in ANCA-associated glomerulonephritis
This study supports serum miRNA profiling as an adjunct noninvasive biomarker for assessing disease activity in AAV-GN. Such an approach could provide complementary information alongside traditional biomarkers and refine the future management of AAV-GN. However, it is important to acknowledge that our actual study cohort was small due to challenging technical aspects of miRNA expression analysis in the serum. Therefore, further research with larger cohorts is required to validate these results and assess their clinical applicability.
Authors
- Matic Bošnjak (ORCID: https://orcid.org/0000-0002-5536-7518)
- Emanuela Boštjančič (ORCID: https://orcid.org/0000-0002-8091-4595)
- Živa Pipan Tkalec
- Nika Kojc (ORCID: https://orcid.org/0000-0003-1893-4349)
- Željka Večerić‐Haler (ORCID: https://orcid.org/0000-0003-3318-9850)
Institutions
- University of Ljubljana (SI)
- Ljubljana University Medical Centre (SI)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1186/s40001-025-02905-9
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Javna Agencija za Raziskovalno Dejavnost RS
- Univerza v Ljubljani
- Univerzitetni Klinični Center Maribor