Cholesterol-to-lymphocyte ratio (CLR)-based nomogram as a prognostic tool in nasopharyngeal carcinoma: a large-scale long-term retrospective study

CLR stands as an independent prognostic factor for NPC patients undergoing CCRT. The CLR-based nomogram (incorporating five independent prognostic factors: age, T stage, N stage, BMI, and CLR) provides a tailored approach to predicting survival, enabling healthcare providers to adjust treatment strategies in accordance with individual risk profiles. Further validation of these findings in external cohorts is necessary, as well as exploration of CLR's clinical utility in directing treatment decisions.

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Publication Details

Journal
European journal of medical research
Published
2025-07-21
DOI
https://doi.org/10.1186/s40001-025-02793-z
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
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article

Cholesterol-to-lymphocyte ratio (CLR)-based nomogram as a prognostic tool in nasopharyngeal carcinoma: a large-scale long-term retrospective study

Si‐Fen Wang, Xin Huang, Yong-Miao Lin, Weiqiong Ni et al.
European journal of medical research
Inflammatory Biomarkers in Disease Prognosis
article

Cholesterol-to-lymphocyte ratio (CLR)-based nomogram as a prognostic tool in nasopharyngeal carcinoma: a large-scale long-term retrospective study

Si‐Fen Wang, Xin Huang, Yong-Miao Lin, Weiqiong Ni, Jing Yuan, Shasha Du, Ao-Qiang Chen, Zhi‐Qing Long, Yu-Ling Zhang, Fangfang Duan, Xinyu Liu, Chao Zhang, Xin Hua, Wen Xia, Xuewen Zhang, Dehuan Xie
article en

Abstract

CLR stands as an independent prognostic factor for NPC patients undergoing CCRT. The CLR-based nomogram (incorporating five independent prognostic factors: age, T stage, N stage, BMI, and CLR) provides a tailored approach to predicting survival, enabling healthcare providers to adjust treatment strategies in accordance with individual risk profiles. Further validation of these findings in external cohorts is necessary, as well as exploration of CLR's clinical utility in directing treatment decisions.

European journal of medical researchVol. 30(1)
Sun Yat-sen University (CN), Shanghai Jiao Tong University (CN), Ruijin Hospital (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial People's Hospital (CN), Guangdong Academy of Medical Sciences (CN), Sun Yat-sen University Cancer Center (CN), Guangdong Provincial People's Hospital (CN), Southern Medical University (CN)
Zero hunger, Good health and well-being
Openalex Percentile: Top 74%
Inflammatory Biomarkers in Disease Prognosis
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