Fractional order breast cancer model with therapy, prevention diagnosis and optimal control based on real data

Cancer is one of the most perilous diseases worldwide, often incurable if not diagnosed in its early stages. Among cancers, breast cancer ranks as the second most lethal, particularly affecting women and contributing to a significant number of fatalities. This work analyzes the breast cancer model in the fractional scenario by incorporating the therapy and prevention diagnosis. The model is subjected to theoretical and numerical investigations to explore the dynamics and predictions of the disease. Furthermore, optimal disease control is presented along with a sensitivity analysis of model parameters. Furthermore, the obtained results are compared with the real data with varying fractional orders, revealing that most of the data points coincide with the fractional order 0.98.

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Publication Details

Journal
Scientific Reports
Published
2025-07-21
DOI
https://doi.org/10.1038/s41598-025-03357-1
Citations
2
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
2.74
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article

Fractional order breast cancer model with therapy, prevention diagnosis and optimal control based on real data

Shaimaa A. M. Abdelmohsen, Sayed Saifullah, Haifa A. Alyousef
2 citations
Scientific Reports
Mathematical Biology Tumor Growth
2.74
article

Fractional order breast cancer model with therapy, prevention diagnosis and optimal control based on real data

Shaimaa A. M. Abdelmohsen, Sayed Saifullah, Haifa A. Alyousef
article en
2 citations

Abstract

Cancer is one of the most perilous diseases worldwide, often incurable if not diagnosed in its early stages. Among cancers, breast cancer ranks as the second most lethal, particularly affecting women and contributing to a significant number of fatalities. This work analyzes the breast cancer model in the fractional scenario by incorporating the therapy and prevention diagnosis. The model is subjected to theoretical and numerical investigations to explore the dynamics and predictions of the disease. Furthermore, optimal disease control is presented along with a sensitivity analysis of model parameters. Furthermore, the obtained results are compared with the real data with varying fractional orders, revealing that most of the data points coincide with the fractional order 0.98.

Scientific ReportsVol. 15(1)
Princess Nourah bint Abdulrahman University (SA), University of Campania "Luigi Vanvitelli" (IT)
Good health and well-being
Openalex Percentile: Top 10%
Mathematical Biology Tumor Growth
2.74
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