Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening
Digital estimates of trophoblastic mosaicism hold clinical significance for informing posttest counseling. Implementing these recommendations could reduce invasive testing for RAT from 0.33% to 0.11%.
Authors
- Katrien De Mulder
- Dieter De Smet (ORCID: https://orcid.org/0000-0001-8810-5808)
- Brigitte Maes (ORCID: https://orcid.org/0009-0004-2301-3370)
- Ellen Geerdens
- Koen Swaerts
- Geert A. Martens (ORCID: https://orcid.org/0000-0003-1208-6289)
- Elke Boone (ORCID: https://orcid.org/0000-0001-6847-8965)
- Guy Froyen (ORCID: https://orcid.org/0000-0002-6671-1572)
- Severine Berden
- Pieter‐Jan Volders (ORCID: https://orcid.org/0000-0002-2685-2637)
- Pauline Herroelen (ORCID: https://orcid.org/0000-0001-8431-520X)
- Henk Louagie
- J.P. Wils
- Annick Daniëls
Institutions
- HOGENT University of Applied Sciences and Arts (BE)
- Ghent University (BE)
- AZ Klina (BE)
- Jessa Hospital (BE)
- AZ Delta (BE)
- AZ Sint-Lucas (BE)
- Hasselt University (BE)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2025-07-21
- DOI
- https://doi.org/10.1093/clinchem/hvaf081
- Citations
- 1
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 3.49