Cytokine responses to respiratory syncytial virus infection in well-differentiated infant nasal epithelial cell cultures
We established methods for obtaining, culturing, differentiating, and infecting iHNE cells, which were safe and highly reproducible. A more efficient RSV replication in infants upper airway cells than in cells from adults could be a factor contributing to the greater disease severity of RSV in infants.
Authors
- Asunción Mejías (ORCID: https://orcid.org/0000-0002-5983-8006)
- Mark E. Peeples (ORCID: https://orcid.org/0000-0002-4582-317X)
- Ki Wook Yun (ORCID: https://orcid.org/0000-0002-0798-6779)
- Susan D. Reynolds (ORCID: https://orcid.org/0000-0003-4754-7858)
- Octavio Ramilo (ORCID: https://orcid.org/0000-0002-0565-5239)
- Phylip Chen (ORCID: https://orcid.org/0000-0001-6090-6320)
Institutions
- St. Jude Children's Research Hospital (US)
- Nationwide Children's Hospital (US)
- Seoul National University (KR)
- The Ohio State University (US)
Publication Details
- Journal
- Clinical and Experimental Vaccine Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.7774/cevr.2025.14.e30
- Citations
- 1
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Seoul National University