Biochemical Profiles in Hypertension: Ferritin, Antioxidant Enzymes, and Mineral Levels in Blood Serum

The aim of this study was to evaluate the level of ferritin and some biochemical indices in patients with hypertension. The total number of samples taken was 90, including 60 from hypertensive patients (Group 1: 30 female patients and 30 male patients) aged between 25 and 55 years, and another 30 specimens from healthy individuals (Group 2: 15 female patients and 15 male patients). Samples were obtained from an open-access repository that aggregates information from multiple sources. Specific collection locations were not disclosed to ensure confidentiality and generalizability of the findings. This study assessed concentrations of ferritin, cholesterol, catalase, malondialdehyde (MDA), peroxidase, nitrite, sodium, and potassium in the blood serum. The results showed that Group 1 has higher levels of serum ferritin than the control group, which are significantly different among male patients, but no significant difference between male and female subjects in the control group. Findings revealed that Group 1 had lower cholesterol levels compared to those without high blood pressure. Catalase levels did not differ significantly between groups, although they were found to be higher in male patients of Group 1. Malondialdehyde level was significantly higher in Group 1 as compared to the control group, while peroxidase activity showed no significant difference between groups. Sodium concentration was significantly greater for Group 1, whereas potassium concentration was the highest in the control group. This demonstrates how these biomarkers could help understand hypertension more clearly and suggests potential research areas requiring closer clinical attention.