Total Pancreatectomy with Islet Auto-transplantation in Chronic Pancreatitis is the Call of our Time.

Introduction: Total pancreatectomy with islet auto-transplantation is a realistic therapeutic choice and an advanced surgical operation for individuals with chronic pancreatitis. The primary purpose of total pancreatectomy with islet auto-transplantation is to alleviate the debilitating pain caused by chronic pancreatitis and thereby significantly improve the quality of life of patients with chronic pancreatitis. Although the permanent loss of the function of the pancreatic endocrine occurs due to total pancreatectomy, it may be substituted by autologous transplantation of islets. Patients receiving total pancreatectomy and Islet Transplantation may be less dependent on insulin than patients receiving total pancreatectomy. This process, although not without some difficulties, has consistently demonstrated promising results in reducing pain, improving glycemic control, mitigating diabetic complications, and enhancing the overall quality of life in patients with chronic pancreatitis. In this article, we review the global experience with Total pancreatectomy with islet auto-transplantation and examine the prospects for its implementation in the Albanian health system. They can alleviate the burden of chronic pancreatitis, improve patients' prognosis, and enhance the country's healthcare system capacity. However, the introduction will also necessitate a strategic transformation of infrastructure, training, and health policy, which is discussed below. Conclusions: Total pancreatectomy with islet auto-transplantation is a novel, effective treatment option for patients with recurrent acute pancreatitis and those with chronic pancreatitis. Its implementation in Albania, while promising, necessitates strategic reforms in infrastructure, training, and health policy. However, if constructed as a secondary project with the aim of institutional support, these reforms can significantly increase the quality of care for patients with chronic pancreatitis in our country.