PSMC3IP as a prognostic biomarker and immunomodulatory regulator in low-grade glioma: insights from multi-omics and methylation analysis

PSMC3IP is overexpressed in LGG and serves as an independent prognostic factor for poor survival. Its involvement in immune regulation and key molecular pathways, including DNA replication, suggests it may be a target for therapeutic strategies in LGG.

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Publication Details

Journal
Neurological Research
Published
2025-07-20
DOI
https://doi.org/10.1080/01616412.2025.2528159
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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PSMC3IP as a prognostic biomarker and immunomodulatory regulator in low-grade glioma: insights from multi-omics and methylation analysis

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PSMC3IP as a prognostic biomarker and immunomodulatory regulator in low-grade glioma: insights from multi-omics and methylation analysis

Yanzheng Gao, Yusheng Chen, Sujie Gu, Hao Wang, Zongye Zhang, Zhendong Liu, Xingbo Cheng, Zhou Sha
article en

Abstract

PSMC3IP is overexpressed in LGG and serves as an independent prognostic factor for poor survival. Its involvement in immune regulation and key molecular pathways, including DNA replication, suggests it may be a target for therapeutic strategies in LGG.

Neurological ResearchVol. 48(2)
Zhengzhou University (CN), Zhengzhou People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 75%
Glioma Diagnosis and Treatment
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