Identification of potential biomarkers and therapeutic targets for cerebral venous thrombosis

This study reveals novel gene networks potentially involved in CVT pathogenesis and prioritizes IL18, BMPR2, and COMT as promising candidates for future therapeutic development. Nonetheless, these findings are based on genetic inference and require further mechanistic and clinical validation.

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Publication Details

Journal
Neurological Research
Published
2025-07-20
DOI
https://doi.org/10.1080/01616412.2025.2532039
Primary Topic
Cerebral Venous Sinus Thrombosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification of potential biomarkers and therapeutic targets for cerebral venous thrombosis

G.H. Zhang, Jiahao Song, Xunming Ji, Guangyu Han et al.
Neurological Research
Cerebral Venous Sinus Thrombosis
article

Identification of potential biomarkers and therapeutic targets for cerebral venous thrombosis

G.H. Zhang, Jiahao Song, Xunming Ji, Guangyu Han, Da Zhou, Jingrun Li, Xiaoming Zhang, Ran Meng
article en

Abstract

This study reveals novel gene networks potentially involved in CVT pathogenesis and prioritizes IL18, BMPR2, and COMT as promising candidates for future therapeutic development. Nonetheless, these findings are based on genetic inference and require further mechanistic and clinical validation.

Neurological Research
Capital University (US), Capital Medical University (CN), Wayne State University (US), Chinese Institute for Brain Research (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 73%
Cerebral Venous Sinus Thrombosis
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