Multilevel Correlates of Same Day Poly-Product Use/Co-Use among Adolescents Who Use Tobacco and Cannabis

Frequent same-day poly-product/drug use is common among adolescents who use tobacco and/or cannabis. Alcohol use, societal concerns, and environmental exposure to secondhand smoke/vape are significant contributors to same-day poly-product/drug use and nicotine and marijuana/THC vape mixing among these adolescents. Findings suggest that while infrequent same-day poly-product/drug use may be more opportunistic and situation-dependent, often occurring in contexts where alcohol is present, frequent use may be more influenced by social contexts and environmental cues. Understanding these complex relationships between substances and high-risk use patterns is crucial for developing effective prevention strategies and treatment approaches for poly-drug use disorders.