Clinicopathological features and prognostic insights of cutaneous versus non-cutaneous angiosarcoma: A retrospective single-center cohort study
C-AS and NC-AS exhibit distinct prognostic profiles, with NC-AS associated with a higher metastatic burden and worse outcomes. Prognostic factors such as tumor grade and metastases at diagnosis influence survival. Multimodal treatment strategies appear beneficial, though recurrence remains a major challenge. Further prospective studies are needed to refine therapeutic approaches and explore emerging targeted therapies.
Authors
- Julia Neuenschwander (ORCID: https://orcid.org/0000-0003-4013-2211)
- Davide Voci (ORCID: https://orcid.org/0000-0001-9573-7029)
- Rolf P. Engelberger
- Tim Sebastian (ORCID: https://orcid.org/0000-0003-0446-2862)
- Riccardo M. Fumagalli (ORCID: https://orcid.org/0000-0002-6794-1986)
- Nils Kucher (ORCID: https://orcid.org/0000-0002-7352-8709)
- Alexandru Grigorean (ORCID: https://orcid.org/0000-0002-4023-0973)
- Franca Lisy
Institutions
- University of Fribourg (CH)
- University Hospital of Zurich (CH)
- Fribourg Development Agency (CH)
- Spital Uster (CH)
Publication Details
- Journal
- Pathology - Research and Practice
- Published
- 2025-07-20
- DOI
- https://doi.org/10.1016/j.prp.2025.156139
- Primary Topic
- Vascular Tumors and Angiosarcomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00