Pubertal mediators of early life stress and age on adolescent alcohol initiation: Analysis by sex
Our findings highlight sex-specific effects of age on alcohol use initiation, with females showing an indirect effect of age on alcohol initiation mediated by pubertal measures, and males showing a direct effect of age. Future studies should investigate sex differences in the interactions of testosterone and PDS with social and individual factors influencing alcohol use initiation. Recognizing the different pathways influencing male and female early adolescent alcohol use initiation can help health providers and parents tailor alcohol prevention strategies to address the needs of their adolescent.
Authors
- Magda Shaheen (ORCID: https://orcid.org/0000-0001-9077-5798)
- Alexandra Donovan (ORCID: https://orcid.org/0009-0001-4655-2615)
- Linda Richter (ORCID: https://orcid.org/0000-0001-7535-8283)
- Theodore C. Friedman (ORCID: https://orcid.org/0000-0001-9555-7626)
- Shervin Assari (ORCID: https://orcid.org/0000-0002-5054-6250)
- Christine E. Grella (ORCID: https://orcid.org/0000-0002-0664-3248)
Institutions
- Neurobehavioral Systems (US)
- East Harlem Tutorial Program (US)
- Charles R. Drew University of Medicine and Science (US)
Publication Details
- Journal
- Psychoneuroendocrinology
- Published
- 2025-07-20
- DOI
- https://doi.org/10.1016/j.psyneuen.2025.107559
- Primary Topic
- Child Abuse and Trauma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of California
- National Institutes of Health
- National Institute on Drug Abuse
- National Institute on Minority Health and Health Disparities