Convenient, direct, metal-free, regioselective and <i>de novo</i> synthesis of 2,4,5-trisubstituted pyrimidines using α-aryl-β, β-ditosyloxy ketones
Current study reflects a regioselective and efficient synthesis of less studied 2,4,5-trisubstituted pyrimidines via geminal ditosyloxy ketones. The methodology reduces the number of synthetic steps and also avoids the use of hazardous reagents.
Authors
- Ravinder Kumar (ORCID: https://orcid.org/0000-0003-0623-3959)
- Ritu Langyan (ORCID: https://orcid.org/0000-0002-7743-2229)
- Raj Kamal (ORCID: https://orcid.org/0000-0002-9403-584X)
- Omkar Bains
- Ashish Kumar (ORCID: https://orcid.org/0000-0003-1315-9718)
Institutions
- Maharishi Markandeshwar University, Mullana (IN)
- Kurukshetra University (IN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj01485a
- Citations
- 1
- Primary Topic
- Synthesis of heterocyclic compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- University Grants Commission
- Kurukshetra University
- Human Resource Development Group