Bidirectional mendelian randomization and single-cell sequencing reveal T cell-mediated causal links between COPD and lung adenocarcinoma
This study analyzed the role of CD4 + T cells in COPD and lung adenocarcinoma and found that the CXCR4 gene may affect lung adenocarcinoma development, providing new insights into the link between COPD and lung adenocarcinoma.
Authors
- Zhe Chi (ORCID: https://orcid.org/0000-0002-8794-1940)
- Yung‐Chih Lai (ORCID: https://orcid.org/0000-0003-1211-4358)
- Dongyu Yang (ORCID: https://orcid.org/0009-0007-0126-9297)
- Xiaozhong Wang (ORCID: https://orcid.org/0000-0001-8658-1931)
- Linfeng Jin
- Meng Cai (ORCID: https://orcid.org/0000-0003-4702-7326)
- Kaili Liao
- Jiarong Wen
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Third Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1097/js9.0000000000002448
- Citations
- 5
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 7.59