Vitamin D levels in stable COPD patients according to the new GOLD staging

Aim: This study investigates Vitamin D3 levels in stable COPD patients according to the new GOLD stages.Material and Methods: 320 stable COPD patients were included in the study.Staging was done according to GOLD 2023 criteria, and the relationship with Vitamin D was examined.Results: The average Vit D3 level of the COPD patients included in the study was 18.49 10.08, with 59.1% having Vit D3 deficiency and 28.1% having Vit D3 insufficiency.According to GOLD 2023 staging, 20.3% of the patients were classified as GOLD A, 26.6% as GOLD B and 53.1% as GOLD E. Significant differences were found between the groups in terms of Vit D3, %FEV1, %FVC, and age.There was a significant negative correlation between Vit D3 levels and exacerbations in the last year and the mMRC dyspnea scale (respectively r = -0.54p < 0.0001, r = -0.43p < 0.0001)).Positive significant correlations were found between Vit D3 levels and %FEV1 and %FVC parameters (respectively r = 0.14 p = 0.004, r = 0.23 p < 0.0001).Discussion: In this study, in stable COPD patients according to GOLD 2023, Vitamin D levels significantly decrease as the severity of the disease increases.