Role of genetics in the age-related testosterone decline in men: a UK Biobank study

Non-genetic factors are strongly associated with age-related BAT decline, whereas genetic predisposition may have a limited role. However, this does not rule out a potential genetic contribution. Our findings offer insight into the relationship between comorbidities and hormonal changes, supporting further research into their roles in T decline and related health risks in aging men.

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Publication Details

Journal
European Journal of Endocrinology
Published
2025-07-14
DOI
https://doi.org/10.1093/ejendo/lvaf143
Citations
1
Primary Topic
Hormonal and reproductive studies
Type
article
Field-Weighted Citation Impact
1.29
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article

Role of genetics in the age-related testosterone decline in men: a UK Biobank study

Michael J. Ziller, Lynn Ogoniak, Julian Varghese, Sarah Sandmann et al.
1 citations
European Journal of Endocrinology
Hormonal and reproductive studies
1.29
article

Role of genetics in the age-related testosterone decline in men: a UK Biobank study

Michael J. Ziller, Lynn Ogoniak, Julian Varghese, Sarah Sandmann, Alexander S. Busch, Nina Neuhaus
article en
1 citations

Abstract

Non-genetic factors are strongly associated with age-related BAT decline, whereas genetic predisposition may have a limited role. However, this does not rule out a potential genetic contribution. Our findings offer insight into the relationship between comorbidities and hormonal changes, supporting further research into their roles in T decline and related health risks in aging men.

European Journal of EndocrinologyVol. 193(2)
University of Münster (DE), University Hospital Münster (DE), Institute of Reproductive Medicine (IN), FH Münster University of Applied Sciences (DE), Otto-von-Guericke-Universität Magdeburg (DE)
Good health and well-being
Openalex Percentile: Top 17%
Hormonal and reproductive studies
1.29
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